Product Description
Product Name Tacrolimus
Synonyms "FK-506 monohydrate
FK 506 Monohydrate
FK-506 monohydrate,Tacrolimus
TacroliMus Monohydrate
15,19-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-[(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propen-1-yl)-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-, hydrate (1:1)
TACROLIMUS
(1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-17-Allyl-1,14-dihydroxy-12-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-propen-2-yl}-23,25-dimethoxy-13,19,21,27-tetramethyl-11,28-dioxa-4-azatr ;icyclo[22.3.1.0]octacos-18-ene-2,3,10,16-tetrone hydrate (1:1)
Tacrolimus (monohydrate)"
CAS NO 109581-93-3
ENIENCS N/A
Molecular Formula C44H71NO13
Molecular Weight 822.033
Melting point 127-129°
Boiling Point 871.7ºC at 760 mmHg
Flash Point 481ºC
Density N/A
Assay 99%
Grade Pharmaceutical Grade
Solubility N/A
Appearance white powder
Storage Keep sealed in a ventilated and dry place, avoid contact with other oxides
Packaging and Shipping Aluminum foil bag, cartons, plastic contain,drums or as required; By Express, by Air, by Sea according to the Amount.
Usage Isofraxidin, a coumarin component derived from Acanthopanax Senticosus, inhibits mMP-7 expression and invasion of human liver cancer cells. Isofraxidin acts on liver cancer cells and inhibits erK1/2 phosphorylation. Isofraxidin attenuated the expression of iNOS and COX-2, and inhibited the formation of TLR4/ myeloid differentiation protein 2 (MD-2) complex.
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