High Quality CAS 75330-75-5 99% High Purity Lovastatin Hot Sale

High Quality CAS 75330-75-5 99% High Purity Lovastatin Hot Sale

Brand:
Hanhong
Place of origin:
China
Model Number:
75330-75-5
Dimension:
0.00 X 0.00 X 0.00 cm
SKU:
75330-75-5
Certification:
ISO 9000/9001/9004/19011: 2000
Minimum Orders:
1kg
Available:
2
Price:
$20
 
 
Ship To (shipping cost):
Canada ($10), United States ($10)
Packing:
bags
Delivery Time:
7-15 days
Payments:
Payments
Guarantee:
Get the item you ordered or get your money back.

Seller Details

Rating:

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Location:
China
Joined:
20 March 2023
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Product Description

CAS No.75330-75-5 Chemical Name:Lovastatin SynonymsMONACOLIN K;MEVINOLIN;LOVASTATION;Lovastatin,Monacolin K;mevlor;msd803;MK-803;Sivlor;LOVALIP;MEVACOR CBNumber:CB7169342 Molecular Formula:C24H36O5 Melting point 175°C alpha D25 +323° (c = 0.5 g in 100 ml acetonitrile) Boiling point 559.2±50.0 °C(Predicted) Density 1.12±0.1 g/cm3(Predicted) vapor pressure 0Pa at 25? refractive index 320 ° (C=0.5, CH3CN) storage temp. -20°C General Description Lovastatin, 2-methylbutanoic acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester, mevinolin,MK-803 (Mevacor) (formerly called mevinolin), is a potentinhibitor of HMG-CoA. The drug was obtained originallyfrom the fermentation products of the fungi Aspergillus terreusand Monascus ruber. Lovastatin was one of two originalHMG-CoA reductase inhibitors. The other drug, mevastatin(formerly called compactin), was isolated from cultures ofPenicillium cillium citrum. Mevastatin was withdrawn fromclinical trials because it altered intestinal morphology in dogs.This effect was not observed with lovastatin. For inhibitoryeffects on HMG-CoA reductase, the lactone ring must be hydrolyzedto the open-ring heptanoic acid. Uses 1. It is as a novel lipid regulating drugs-The inhibitor of HMG-CoA (?-hydroxy, ?-methyl-glutaryl coenzyme A) reductase. It can significantly reduced serum total cholesterol level. After oral administration, it is hydrolyzed into corresponding ?-hydroxy acid by 3-hydroxy-3-methylglutaryl coenzyme A reductase, and thus inhibiting the cholesterol biosynthesis. It is clinically used for treating heterozygous familial hypercholesterolemia, severe or mild hypercholesterolemia and light. It can also as an ancillary drug of dietary treatment for reducing the levels of excessively cholesterol and low-density protein cholesterol. 2. It is a cardiovascular systematic drug which can prevent the development of atherosclerosis and reduce the risk of myocardial infarction.

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