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Product Description
Contact Information
Gem Jiang
Email:GEM@whmulei.com
Tel/whatsapp/signal/ telegram:0086 19831951097
Product basic information:
Name:Procaine
CAS No.:59-46-1
Density 1.1±0.1 g/cm3
Boiling Point 373.6±22.0 °C at 760 mmHg
Melting Point 61oC
Molecular Formula C13H20N2O2
Molecular Weight 236.310
Flash Point 179.8±22.3 °C
Exact Mass 236.152481
PSA 55.56000
LogP 2.36
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.543
Usage
Procaine is a local anesthetic drug of the amino ester group, Procaine acts through multiple targets.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM [1]. Procaine is a DNA-demethylating agent that produces a 40% reduction in 5-methylcytosine DNA content as determined by high-performance capillary electrophoresis or total DNA enzyme digestion. Procaine can also demethylate densely hypermethylated CpG islands. Procaine also has growth-inhibitory effects in these cancer cells, causing mitotic arrest [2]. Procaine functions as an excitant of limbic system cells, and that procaine alters synaptic transmission in some, but not all, output pathways from the amygdale [3].
